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Support research work in Cambridge to repair myelin and preserve function in multiple sclerosis

Dr Nick Cunniffe leads the Cambridge Clinical Remyelination Research Group, a team dedicated to developing treatments that can reverse damage in MS.

MS is a lifelong neurological condition affecting over 150,000 people in the UK, causing disability through the loss of myelin - the protective sheath around nerve fibres. This damage disrupts communication within the brain and spinal cord, leading to physical, cognitive, and visual impairments.

The group’s research focuses on remyelination: repairing this damaged myelin to restore nerve function and prevent or reverse disability. In Cambridge, the team is running innovative clinical trials to test promising drugs that enhance the brain’s natural repair processes. They are also developing advanced imaging and blood-based tests to measure remyelination more precisely and efficiently. These approaches will help identify which treatments work, for whom, and at what time.

Supporting this research will accelerate the development of therapies that could delay, prevent, or reverse disability associated with multiple sclerosis.

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Head of Development, Brain and Mind Health

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