Support research developing new treatments for multiple sclerosis through remyelination and neuroimmunology
Professor Alasdair Coles is the Head of the Department of Clinical Neurosciences.
He also leads the Cambridge Clinical MS Research Group, a team dedicated to developing treatments that can repair myelin and reverse disability in MS.
MS is a lifelong neurological condition affecting over 150,000 people in the UK, causing progressive disability through immune-mediated damage to myelin, the protective sheath surrounding nerve fibres. For decades, treatments have focused on suppressing this inflammation, but many people with MS still experience worsening disability over time.
The group's research focuses on the next frontier in MS treatment: remyelination. The team runs innovative clinical trials testing whether repurposed drugs, including the diabetes medicine metformin and the antihistamine clemastine, can stimulate the brain's own stem cells to repair damaged myelin and reverse disability. They are also investigating immunotherapy approaches for autoimmune conditions of the brain.
Supporting this research will help unlock treatments that go beyond controlling MS to actively repairing the damage it causes.
Next steps
You can support this research by giving a gift online now or to discuss your philanthropic objectives, please contact:
Make a gift now
Make a gift now to support A Coles Research Group by credit or debit card, or set up a direct debit:
Or, find out about other ways to give.
Display none
This opportunity is part of
Related stories
Philanthropic giving is at the heart of the success of the Collegiate University, enabling us to make discoveries that change the world and to ensure that our students receive an unrivalled education. Cambridge owes its world-leading excellence in research and teaching to the generosity of its supporters. Our history is synonymous with a history of far-sighted benefaction, and the same is as true today as it has ever been.
